BET inhibitors enhance the anti-cancer effect of etoposide by suppressing the MRN-ATM axis in the DNA damage response

Genes Dis. 2022 Dec 31;11(1):19-22. doi: 10.1016/j.gendis.2022.12.001. eCollection 2024 Jan.

Zhenhai Li¹, Wenchao Xu², Feng Chen¹, Jun Zhang¹, Wei-Guo Zhu^{1

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¹ Guangdong Key Laboratory of Genome Instability and Human Disease Prevention, Department of Biochemistry and Molecular Biology, Shenzhen University School of Medicine, Shenzhen, Guangdong 518055, China.
² School of Pharmaceutical Sciences, Shenzhen University Health Science Center, Shenzhen, Guangdong 518055, China.
³ Base for International Science and Technology Cooperation: Carson Cancer Stem Cell Vaccines R&D Center, International Cancer Center, Shenzhen University Health Science Center, Shenzhen, Guangdong 518055, China.
⁴ Shenzhen Bay Laboratory, Shenzhen University School of Medicine, Shenzhen, Guangdong 518055, China.
⁵ Marshall Laboratory of Biomedical Engineering, Shenzhen University School of Medicine, Shenzhen, Guangdong 518055, China.

No abstract available