Blastic Plasmacytoid Dendritic Cell Neoplasm with Lung Involvement and Cytopenia: A Case Report and a Literature Review

Fang Liu; Fei Qi; Jingya Zhang; Yaqi Tan; Xiuying Zhang

doi:10.2147/CCID.S414326

Blastic Plasmacytoid Dendritic Cell Neoplasm with Lung Involvement and Cytopenia: A Case Report and a Literature Review

Clin Cosmet Investig Dermatol. 2023 Aug 11:16:2211-2216. doi: 10.2147/CCID.S414326. eCollection 2023.

Authors

Fang Liu¹, Fei Qi², Jingya Zhang¹, Yaqi Tan¹, Xiuying Zhang¹

Affiliations

¹ Department of Dermatology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People's Republic of China.
² Department of Dermatology, Peking Union Medical College Hospital, Beijing, People's Republic of China.

Abstract

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a hostile cutaneous malignancy with dismal prognosis and unknown etiology with rarity. Most patients received traditional chemotherapy only has one year of median survival time. This article reports an 81-year-old male patient with BPDCN who presented with skin manifestations and was diagnosed with positive CD4, CD56, and CD123 immunohistochemical results. Systematic examination revealed lung involvement and cytopenia.

Keywords: blastic plasmacytoid dendritic cell neoplasm; cytopenia; lung involvement; pathological feature; prognosis; treatment.

Publication types

Case Reports

Grants and funding

This study was supported by the National Natural Science Foundation of China (Fund No. 82273551).