Gastric Varices Rupture due to Splenic Vein Obstruction Associated with Autoimmune Pancreatitis

Intern Med. 2024 Apr 1;63(7):943-948. doi: 10.2169/internalmedicine.2419-23. Epub 2023 Aug 16.

Abstract

A 60-year-old man with a high IgG4 level was found to have pancreatic tail enlargement on computed tomography (CT), and autoimmune pancreatitis (AIP) was confirmed by a histological diagnosis. He was treated with prednisolone for one year and seven months, at which point his treatment finished. Four months later, however, he had hematemesis from gastric varices. CT showed recurrence of pancreatic tail enlargement with obstruction of the splenic artery and vein and formation of collateral blood vessels to the gastric fornix. Endoscopic injection sclerotherapy was performed, and he underwent splenectomy. This case highlights the importance of paying attention to peripancreatic vascular abnormalities during follow-up of AIP patients.

Keywords: autoimmune pancreatitis; splenic vein; varices.

Publication types

  • Case Reports

MeSH terms

  • Autoimmune Pancreatitis* / complications
  • Esophageal and Gastric Varices* / complications
  • Esophageal and Gastric Varices* / therapy
  • Humans
  • Male
  • Middle Aged
  • Pancreatitis* / complications
  • Pancreatitis* / diagnostic imaging
  • Splenic Diseases* / diagnosis
  • Splenic Vein / diagnostic imaging
  • Splenic Vein / pathology
  • Vascular Diseases* / complications