Autophagy in intestinal epithelial cells prevents gut inflammation

Abstract

Intestinal epithelial cells form the largest barrier in the body, separating us from the outside world. Here, we review recent findings that highlight the role of autophagy in the cell-intrinsic response of the epithelial cells to the harsh intestinal environment and how they shape host physiology.

Keywords: autophagy; epithelium; inflammation; inflammatory bowel diseases; intestinal barrier; intestine.