Combining methylated SEPTIN9 and RNF180 plasma markers for diagnosis and early detection of gastric cancer

Yongzhan Nie; Xianchun Gao; Xiqiang Cai; Zhen Wu; Qiaoyi Liang; Guobing Xu; Na Liu; Peng Gao; Jingyu Deng; Hongzhi Xu; Zhanlong Shen; Changqi Cao; Fenrong Chen; Nannan Zhang; Yongxi Song; Mingjun Sun; Chengyin Liu; Guangpeng Zhou; Weili Han; Jianhua Dou; Huahong Xie; Liping Yao; Zhiguo Liu; Gang Ji; Xin Wang; Qingchuan Zhao; Lei Shang; Daiming Fan; Xiaoliang Han; Jianlin Ren; Han Liang; Zhenning Wang; Jinhai Wang; Qi Wu; Jun Yu; Kaichun Wu; MAGIS Study Group

doi:10.1002/cac2.12478

Combining methylated SEPTIN9 and RNF180 plasma markers for diagnosis and early detection of gastric cancer

Cancer Commun (Lond). 2023 Nov;43(11):1275-1279. doi: 10.1002/cac2.12478. Epub 2023 Aug 16.

Authors

Yongzhan Nie^#¹, Xianchun Gao^#¹, Xiqiang Cai^#², Zhen Wu^#³, Qiaoyi Liang⁴, Guobing Xu⁵, Na Liu⁶, Peng Gao⁷, Jingyu Deng⁸, Hongzhi Xu⁹, Zhanlong Shen¹⁰, Changqi Cao⁵, Fenrong Chen⁶, Nannan Zhang¹, Yongxi Song⁷, Mingjun Sun¹¹, Chengyin Liu³, Guangpeng Zhou³, Weili Han¹, Jianhua Dou¹, Huahong Xie¹, Liping Yao¹, Zhiguo Liu¹, Gang Ji¹, Xin Wang², Qingchuan Zhao¹, Lei Shang¹², Daiming Fan¹, Xiaoliang Han³, Jianlin Ren⁹, Han Liang⁸, Zhenning Wang⁷, Jinhai Wang⁶, Qi Wu⁵, Jun Yu⁴, Kaichun Wu¹; MAGIS Study Group

Affiliations

¹ State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, Shaanxi, P. R. China.
² Department of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, P. R. China.
³ BioChain (Beijing) Science & Technology Inc., Beijing, P. R. China.
⁴ Department of Medicine and Therapeutics, Institute of Digestive Disease, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, P. R. China.
⁵ Department of Endoscopy Center, Peking University Cancer Hospital & Institute, Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Beijing, P. R. China.
⁶ Department of Gastroenterology, the Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.
⁷ Department of Surgical Oncology and General Surgery, Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, P. R. China.
⁸ Department of Gastric Surgery, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin, P. R. China.
⁹ Department of Gastroenterology, Zhongshan Hospital, Xiamen University, Xiamen, Fujian, P. R. China.
¹⁰ Department of Gastrointestinal Surgery, Peking University People's Hospital, Beijing, P. R. China.
¹¹ Department of Endoscope, The First Hospital Affiliated to China Medical University, Shenyang, Liaoning, P. R. China.
¹² Department of Health Statistics, School of Preventive Medicine, Fourth Military Medical University, Xi'an, Shaanxi, P. R. China.

^# Contributed equally.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Cytoskeletal Proteins
DNA Methylation
Humans
Promoter Regions, Genetic
Stomach Neoplasms* / diagnosis
Stomach Neoplasms* / genetics
Ubiquitin-Protein Ligases / genetics

Substances

Cytoskeletal Proteins
RNF180 protein, human
Ubiquitin-Protein Ligases