Menstrual cycle abnormalities in women with inflammatory bowel disease and effects of biological therapy on gynecological pathology

Vaidota Malinauskiene; Anastasija Zuzo; Valentina Liakina; Edita Kazenaite; Ieva Stundiene

doi:10.12998/wjcc.v11.i21.4989

Menstrual cycle abnormalities in women with inflammatory bowel disease and effects of biological therapy on gynecological pathology

World J Clin Cases. 2023 Jul 26;11(21):4989-4995. doi: 10.12998/wjcc.v11.i21.4989.

Authors

Vaidota Malinauskiene¹, Anastasija Zuzo², Valentina Liakina^{1

3}, Edita Kazenaite¹, Ieva Stundiene¹

Affiliations

¹ Clinic of Gastroenterology, Nephrourology and Surgery, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius 01513, Lithuania.
² Faculty of Medicine, Vilnius University, Vilnius 01513, Lithuania.
³ Department of Chemistry and Bioengineering, Faculty of Fundamental Sciences, Vilnius Tech, Vilnius 10223, Lithuania. valentina.liakina@santa.lt.

Abstract

Inflammatory bowel disease (IBD) is a chronic condition that affects young individuals in their reproductive years. It may have long-term implications on their reproductive, sexual, and mental health. IBD has been related to menstrual abnormalities. Furthermore, the administration of biological therapy can also result in gynecological issues in addition to the disease itself. The purpose of this review was to present potential menstrual cycle problems in patients with IBD, as well as the impact of adalimumab and other anti-tumor necrosis factor medications on gynecological pathology.

Keywords: Adalimumab; Anti-tumor necrosis factor-α; Inflammatory bowel disease; Infliximab; Menstrual disorders.

Publication types

Review