Clinical and patient-reported outcomes from the first 4 years of a Psoriasis Biologics Registry in Singapore

Exp Dermatol. 2023 Nov;32(11):2023-2028. doi: 10.1111/exd.14910. Epub 2023 Aug 16.

Abstract

Interim analysis of the National Skin Centre Singapore Psoriasis Biologics Registry (SINGPSOR) from August 2017 to May 2021, in which 58 patients were analysed, showing that those receiving biologic treatment had significantly more severe psoriasis based on PASI (Psoriasis Area and Severity Index), BSA (body surface area) and PGA (Physician Global Assessment) measures at baseline, demonstrated a statistically non-significant trend towards greater improvement with treatment, and had a lower percentage of adverse events compared to those receiving conventional systemic therapy. Future analyses of SINGPSOR, with larger sample size and longer follow-up, will be invaluable to further characterize these patients and their treatment outcomes.

Keywords: adalimumab; biologics; psoriasis; registries; ustekinumab.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adalimumab / therapeutic use
  • Biological Products* / therapeutic use
  • Humans
  • Patient Reported Outcome Measures
  • Psoriasis* / chemically induced
  • Psoriasis* / drug therapy
  • Registries
  • Severity of Illness Index
  • Singapore
  • Treatment Outcome

Substances

  • Biological Products
  • Adalimumab