Magnesium deficit decreases nitric oxide production and oxidative stress, but calcium efflux in VSMC enhances proliferation, migration, and remodelling. These pathways contribute to cardiovascular disorders, hypertension, insulin resistance, sodium retention, fluid retention, and blood volume. Magnesium supplements could be beneficial.
Keywords: Cardiovascular health; Endothelial function; Hypertension; Magnesium; Magnesium Supplementation.
© 2023. The Author(s), under exclusive licence to The Japanese Society of Hypertension.