The 2023 Annual Review Issue of The Journal of Pathology, Recent Advances in Pathology, contains 12 invited reviews on topics of current interest in pathology. This year, our subjects include immuno-oncology and computational pathology approaches for diagnostic and research applications in human disease. Reviews on the tissue microenvironment include the effects of apoptotic cell-derived exosomes, how understanding the tumour microenvironment predicts prognosis, and the growing appreciation of the diverse functions of fibroblast subtypes in health and disease. We also include up-to-date reviews of modern aspects of the molecular basis of malignancies, and our final review covers new knowledge of vascular and lymphatic regeneration in cardiac disease. All of the reviews contained in this issue are written by expert groups of authors selected to discuss the recent progress in their particular fields and all articles are freely available online (https://pathsocjournals.onlinelibrary.wiley.com/journal/10969896). © 2023 The Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
Keywords: DNA damage repair; VEGF; advanced analytics; apoptosis; artificial intelligence; biomarkers; breast cancer; cancer; cancer-associated fibroblasts; cardiac regeneration; cell cycle arrest; cell plasticity; cellular senescence; clinical trials; computational pathology; copy number alterations; deep learning; digital pathology; endothelial cells; evolution; exosomes; extracellular vesicles; fibroblast heterogeneity; fibrosis; genomic complexity; guidelines; heart failure; histopathology; image analysis; immune checkpoint inhibitors; immunotherapy; immunotherapy failure; keloid scar; lineage tracing; lymphangiogenesis; machine learning; microvesicles; mutations; myocardial infarction; neovascularisation; oncogenic drivers; pancreatic cancer; patient-derived models; pitfalls; prognostic biomarker; quiescence; sarcomagenesis; sarcomas; secondary genetic alterations; senescence escape; senolytics; single cell sequencing; skin; spatial profiling; structural variants; triple-negative breast cancer; tumour heterogeneity; tumour microenvironment; tumour-infiltrating lymphocytes; whole slide images; wound healing.
© 2023 The Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.