Modeling of the chest wall response to prolonged bracing in pectus carinatum

PLoS One. 2023 Aug 14;18(8):e0288941. doi: 10.1371/journal.pone.0288941. eCollection 2023.

Abstract

Pectus carinatum is a chest wall deformity that is often treated through the wearing of an external brace. The treatment of the deformity could benefit from a greater understanding of chest wall characteristics under prolonged loading. These characteristics are difficult to model directly but empirical studies can be used to create statistical models. 185 patients from 2018-2020 received bracing treatment. Data on the severity of the deformity, treatment pressures, and time of wear were recorded at the first fitting and all subsequent follow-up visits. This data was analyzed using a statistical mixed effects model to identify significant measures and trends in treatment. These models were designed to help quantify changes in chest wall characteristics through prolonged bracing. Two statistical models were created. The first model predicts the change in the amount of pressure to correct the deformity after bracing for a given time and pressure. The second model predicts the change in pressure response by the body on the brace after bracing for a given time and pressure. These models show a high significance in the amount of pressure and time to the changes in the chest wall response. Initial deformity severity is also significant in changes to the deformity. The statistical models predict general trends in pectus carinatum brace treatment and can assist in creating treatment plans, motivating patient compliance, and can inform the design of future treatment systems.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Braces
  • Humans
  • Patient Compliance
  • Pectus Carinatum* / therapy
  • Thoracic Wall*
  • Treatment Outcome

Grants and funding

Funded Study: BS, VH, VG, and LH received a funded research contract via payments to their respective institutions from Zimmer Biomet. The funding institution website is zimmerbiomet.com. NO, the funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.