Engineering the endometrium

Shelly R Peyton

doi:10.1016/j.medj.2023.07.009

Engineering the endometrium

Med. 2023 Aug 11;4(8):495-496. doi: 10.1016/j.medj.2023.07.009.

Author

Shelly R Peyton¹

Affiliation

¹ Department of Chemical Engineering, University of Massachusetts Amherst, Amherst, MA 01003, USA; Molecular and Cellular Biology Graduate Program, University of Massachusetts Amherst, Amherst, MA 01003, USA; Department of Biomedical Engineering, University of Massachusetts Amherst, Amherst, MA 01003, USA; Institute for Applied Life Sciences, University of Massachusetts Amherst, Amherst, MA 01003, USA. Electronic address: speyton@umass.edu.

PMID: 37572649
DOI: 10.1016/j.medj.2023.07.009

Abstract

Endometrial tissue is a dynamic environment that regenerates alongside the menstrual cycle and in response to sex hormones. This month in Med, Gnecco and colleagues¹ present an innovative, synthetic model of endometrial environment that supports long-term cultures, simulates a 28-day menstrual cycle, and could be employed to investigate reproductive pathophysiology.

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MeSH terms

Endometrium*
Epithelium
Female
Humans
Menstrual Cycle*
Reproduction