Vitamin D Intake and Serum Levels in Pregnant and Postpartum Women

Nutrients. 2023 Aug 7;15(15):3493. doi: 10.3390/nu15153493.

Abstract

Maternal vitamin D deficiency, which is highly prevalent in pregnant women in Europe, is linked to adverse health effects for both the mother and child. The objective was to assess vitamin D status in pregnant women by evaluating their dietary and supplemental vitamin D intake, serum vitamin D levels, parathyroid hormone levels, and lifestyle factors. This cross-sectional study, with a total of 735 participants (145 pregnant and 590 up to the seventh day postpartum), took place in Latvia. Blood samples, a food frequency questionnaire, and medical documentation were used for data collection. The median serum vitamin D concentration was 34.0 ng/mL, with pregnant women having higher levels (42.9 ng/mL) than postpartum women (31.8 ng/mL). There was no association between vitamin D serum concentration and dietary intake of vitamin D (p > 0.05), whereas there was a significant correlation with use of vitamin D supplements (r = 0.41; p < 0.001 in pregnant women and r = 0.35; p < 0.001 in postpartum women). This study demonstrated that a minority of pregnant women (21.9%) had optimal serum vitamin D concentration (>45 ng/mL), and diet had no significant impact on vitamin D levels. Thus, our proposed recommendation for vitamin D intake during pregnancy was 63 mcg (2500 IU) year-round for optimal levels in pregnant women in Northeastern Europe.

Keywords: dietary intake; pregnancy; supplementation; vitamin D.

MeSH terms

  • Child
  • Cross-Sectional Studies
  • Dietary Supplements
  • Female
  • Humans
  • Nutritional Status
  • Postpartum Period
  • Pregnancy
  • Pregnant Women
  • Vitamin D Deficiency* / epidemiology
  • Vitamin D*
  • Vitamins

Substances

  • Vitamin D
  • Vitamins