Nutritional Strategies for the Prevention and Management of Cow's Milk Allergy in the Pediatric Age

Nutrients. 2023 Jul 26;15(15):3328. doi: 10.3390/nu15153328.

Abstract

Cow's milk allergy (CMA) is one of the most common pediatric food allergies. The prevalence and severity of CMA have increased dramatically in the last decades, under the pressure of environmental factors in genetically predisposed individuals. Among the environmental influences, nutritional factors play a crucial role. Diet is the most modifiable factor, representing a potential target for the prevention and treatment of CMA. In this review, we report the most scientific-based nutritional strategies for preventing and managing pediatric CMA. In addition, we propose the most complete supplement of compounds able to prevent nutrient deficiencies in CMA pediatric patients and to positively influence the disease course.

Keywords: Mediterranean diet; food allergy; gut microbiome; immunonutrition.

Publication types

  • Review

MeSH terms

  • Animals
  • Cattle
  • Diet
  • Dietary Supplements
  • Female
  • Food Hypersensitivity* / prevention & control
  • Milk Hypersensitivity* / epidemiology
  • Milk Hypersensitivity* / prevention & control
  • Prevalence

Grants and funding

Funder: Project funded under the National Recovery and Resilience Plan (NRRP), Mission 4 Component 2 Investment 1.3—Call for tender No. 341 of 15 March 2022 of Italian Ministry of University and Research funded by the European Union—NextGenerationEU; Award Number: Project code PE00000003, Concession Decree No. 1550 of 11 October 2022 adopted by the Italian Ministry of University and Research, CUP D93C22000890001, Project title “ON Foods—Research and innovation network on food and nutrition Sustainability, Safety and Security—Working ON Foods”.