Fever and dyspnea after anti-Covid-19 vaccination: a challenging diagnosis

Intern Emerg Med. 2024 Apr;19(3):757-760. doi: 10.1007/s11739-023-03390-w. Epub 2023 Aug 11.

Abstract

There is still little information regarding the long-term safety of the vaccines. We report a case of new-onset adult-onset Still's disease (AOSD) that occurred following Covid-19 vaccination. This patient went to the emergency room with dyspnea from the last two weeks and bilateral swellings that occurred several weeks after the first vaccination. Based on the symptoms and laboratory results, we suspected AOSD. Considering the time relationship between Covid-19 vaccination and AOSD onset in our patient, and possible mechanisms linking vaccination with the onset of autoimmune disorders, physicians should consider adverse events from Covid-19 vaccination and assess the benefits and risks of vaccination for each patient.

Publication types

  • Case Reports

MeSH terms

  • COVID-19 / complications
  • COVID-19 / prevention & control
  • COVID-19 Vaccines* / adverse effects
  • Dyspnea* / etiology
  • Fever* / chemically induced
  • Fever* / etiology
  • Humans
  • Male
  • Middle Aged
  • Still's Disease, Adult-Onset / diagnosis
  • Vaccination / adverse effects

Substances

  • COVID-19 Vaccines