Persistent peritonitis in peritoneal dialysis: a comphrenesive review of recurrent, relapsing, refractory, and repeat peritonitis

Int Urol Nephrol. 2024 Feb;56(2):583-595. doi: 10.1007/s11255-023-03731-w. Epub 2023 Aug 10.

Abstract

Peritonitis is a major cause of morbidity and technique failure in patients receiving peritoneal dialysis. Complicated peritonitis that manifests as multiple or unresolving episodes is classified as refractory, recurrent, relapsing, or repeat peritonitis, and often possesses higher risk of technique failure and mortality as well as lower complete cure rates than primary or uncomplicated episodes. While these peritonitis subtypes affect a considerable portion of PD patients, details regarding their epidemiology, pathogenesis, diagnosis, clinical sequelae, and management have not yet been fully elucidated. Improved clinical awareness and understanding of complicated peritonitis subtypes is crucial to ensure optimal management for these patients; thus, we consolidate and report the pertinent findings of recent literature on these four entities.

Keywords: Peritoneal dialysis; Peritonitis; Recurrent; Refractory; Relapsing; Repeat.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Humans
  • Peritoneal Dialysis* / adverse effects
  • Peritoneal Dialysis* / methods
  • Peritonitis* / epidemiology

Substances

  • Anti-Bacterial Agents