Transient non-coeliac gluten sensitivity (NCGS) with markedly reduced villous height/crypt depth ratio

Charlotte Williams; Nicole Smith; Kamran Rostami

doi:10.22037/ghfbb.v16i2.2755

Transient non-coeliac gluten sensitivity (NCGS) with markedly reduced villous height/crypt depth ratio

Gastroenterol Hepatol Bed Bench. 2023;16(2):222-224. doi: 10.22037/ghfbb.v16i2.2755.

Authors

Charlotte Williams¹, Nicole Smith², Kamran Rostami¹

Affiliations

¹ Department of Gastroenterology, MidCentral DHB, Palmerston North, New Zealand.
² Department of Pathology, MidCentral DHB, Palmerston North, New Zealand.

Abstract

There is no confident evidence in the current literature to show or demonstrate that non-coeliac gluten sensitivity (NCGS) exclusively presents with mild or nearly normal duodenal mucosal abnormality. Gluten sensitive patients with negative serology and severe mucosal changes are labelled with the term seronegative coeliac disease (SNCS). There might be at least some overlap between NCGS and SNCD. Transient gluten sensitivity with severe mucosal changes without CD have been previously reported like in our case.

Keywords: Coeliac disease; Histology; Non-coeliac gluten sensitivity.

Publication types

Case Reports