Vitamin B12 deficiency in an infant with neurological and hematological findings: A case report

Clin Case Rep. 2023 Aug 7;11(8):e7770. doi: 10.1002/ccr3.7770. eCollection 2023 Aug.

Abstract

Key clinical message: It is important for pregnant and breastfeeding women who adhere to a strict vegetarian diet to take appropriate steps to avoid vitamin B12 deficiency in their infants.

Abstract: Vitamin B12 deficiency is rare during infancy. The initial symptoms of this deficiency are subtle and may include irritability, failure to thrive with a decline in growth rate, apathy, anorexia, refusal of solid foods, megaloblastic anemia, and developmental regression. The case presented here involves an 8-month-old male infant who showed neurological symptoms such as decreased activity, increased drowsiness, and reduced interaction with parents, which were ultimately linked to a deficiency of cobalamin (vitamin B12). Early recognition of this condition is critical because it is reversible. Therefore, pregnant and lactating women who follow a strict vegetarian diet should take necessary measures to prevent vitamin B12 deficiency in infants.

Keywords: cobalamin; early childhood; infant; neurological symptoms; vitamin B12.

Publication types

  • Case Reports