Management of type 2 diabetes in pregnancy: a narrative review

Front Endocrinol (Lausanne). 2023 Jul 21:14:1193271. doi: 10.3389/fendo.2023.1193271. eCollection 2023.

Abstract

The prevalence of type 2 diabetes (T2DM) at reproductive age is rising. Women with T2DM have a similarly high risk for pregnancy complications as pregnant women with type 1 diabetes. To reduce adverse pregnancy and neonatal outcomes, such as preeclampsia and preterm delivery, a multi-target approach is necessary. Tight glycemic control together with appropriate gestational weight gain, lifestyle measures, and if necessary, antihypertensive treatment and low-dose aspirin is advised. This narrative review discusses the latest evidence on preconception care, management of diabetes-related complications, lifestyle counselling, recommendations on gestational weight gain, pharmacologic treatment and early postpartum management of T2DM.

Keywords: management; peripartum; postpartum Frans (standard); preconception; pregnancy; type 2 diabetes mellitus.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Diabetes Mellitus, Type 1* / complications
  • Diabetes Mellitus, Type 2* / complications
  • Female
  • Gestational Weight Gain*
  • Humans
  • Infant, Newborn
  • Pregnancy
  • Pregnancy Complications* / epidemiology
  • Reproduction

Grants and funding

KB is the recipient of a “Fundamenteel Klinisch Navorserschap FWO Vlaanderen” (1800220N).