Cardiac Metastatic Melanoma Causing Ventricular Arrhythmias Through Impaired Coronary Artery Vasodilation

Alyssa L Chang; Devang R Amin; Kent S Brummel; Michael J Shea

doi:10.1016/j.jaccas.2023.101914

Cardiac Metastatic Melanoma Causing Ventricular Arrhythmias Through Impaired Coronary Artery Vasodilation

JACC Case Rep. 2023 Jun 13:18:101914. doi: 10.1016/j.jaccas.2023.101914. eCollection 2023 Jul 19.

Authors

Alyssa L Chang¹, Devang R Amin², Kent S Brummel², Michael J Shea²

Affiliations

¹ Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
² Department of Cardiology, University of Michigan, Ann Arbor, Michigan, USA.

Abstract

Melanoma is an aggressive malignant disease with a high rate of cardiac metastasis. There is a reported association between myocardial tumor invasion and ventricular arrhythmias. We present a case of cardiac metastatic melanoma causing ventricular arrhythmias through a novel mechanism of encasement of coronary arteries leading to reduced myocardial perfusion. (Level of Difficulty: Intermediate.).

Keywords: cancer; computed tomography; electrocardiogram; electrophysiology; imaging; myocardial ischemia; nuclear medicine; positron emission tomography; ventricular tachycardia.