RUNX1 promotes mitophagy and alleviates pulmonary inflammation during acute lung injury

Xiaoju Tang; Lichun Zhong; Xin Tian; Ying Zou; Silu Hu; Jia Liu; Ping Li; Min Zhu; Fengming Luo; Huajing Wan

doi:10.1038/s41392-023-01520-6

RUNX1 promotes mitophagy and alleviates pulmonary inflammation during acute lung injury

Signal Transduct Target Ther. 2023 Aug 7;8(1):288. doi: 10.1038/s41392-023-01520-6.

Authors

Xiaoju Tang^{1

2}, Lichun Zhong², Xin Tian², Ying Zou², Silu Hu², Jia Liu^{1

2}, Ping Li^{1

2}, Min Zhu^{1

2}, Fengming Luo^{3

4}, Huajing Wan^{5

6}

Affiliations

¹ Department of Respiratory and Critical Care Medicine, Clinical Research Center for Respiratory Diseases, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, 610041, Chengdu, China.
² Laboratory of Pulmonary Immunology and Inflammation, Frontiers Science Center for Disease-related Molecular Network, Sichuan University, No. 2222 Xin Chuan Road, 610200, Chengdu, Sichuan, China.
³ Department of Respiratory and Critical Care Medicine, Clinical Research Center for Respiratory Diseases, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, 610041, Chengdu, China. fengmingluo@outlook.com.
⁴ Laboratory of Pulmonary Immunology and Inflammation, Frontiers Science Center for Disease-related Molecular Network, Sichuan University, No. 2222 Xin Chuan Road, 610200, Chengdu, Sichuan, China. fengmingluo@outlook.com.
⁵ Department of Respiratory and Critical Care Medicine, Clinical Research Center for Respiratory Diseases, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, 610041, Chengdu, China. wanhuajing1974@wchscu.cn.
⁶ Laboratory of Pulmonary Immunology and Inflammation, Frontiers Science Center for Disease-related Molecular Network, Sichuan University, No. 2222 Xin Chuan Road, 610200, Chengdu, Sichuan, China. wanhuajing1974@wchscu.cn.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Acute Lung Injury* / genetics
Core Binding Factor Alpha 2 Subunit / genetics
Humans
Mitophagy / genetics
Pneumonia* / genetics

Substances

Core Binding Factor Alpha 2 Subunit
RUNX1 protein, human