Chemistry and Bioactivity of the Genus Persea - A Review

Chem Biodivers. 2023 Sep;20(9):e202300947. doi: 10.1002/cbdv.202300947. Epub 2023 Aug 22.

Abstract

This review provides the first comprehensive appraisal of bioactive compounds and their biological activities in Persea species from 1950 to 2023. Relevant articles from reputable databases, including PubMed, Web of Science, Science Direct and Google Scholar were collected, leading to the isolation of about 141 metabolite compounds, mainly flavonoids, terpenoids, fatty alcohols, lignoids, and γ-lactone derivatives. These compounds exhibit diverse biological activities, including insecticidal, antifeedant, nematicidal, antibacterial, antifungal, antiviral, cytotoxic, anti-inflammatory, and antioxidant properties. The review emphasizes the significant chemical and pharmacological potential of different Persea species, encouraging further research in various fields and medicine. Valuable insights into potential applications of Persea plants are provided.

Keywords: Lauraceae; Persea; biological activity; natural products; pharmacological potential.

Publication types

  • Review

MeSH terms

  • Anti-Inflammatory Agents / pharmacology
  • Antifungal Agents
  • Ethnopharmacology
  • Persea*
  • Phytochemicals / chemistry
  • Phytotherapy
  • Plant Extracts* / chemistry

Substances

  • Plant Extracts
  • Anti-Inflammatory Agents
  • Antifungal Agents
  • Phytochemicals