Germplasm resources and secondary metabolism regulation in Reishi mushroom (Ganoderma lucidum)

Xinyu He; Yiwen Chen; Zhenhao Li; Ling Fang; Haimin Chen; Zongsuo Liang; Ann Abozeid; Zongqi Yang; Dongfeng Yang

doi:10.1016/j.chmed.2023.01.005

Germplasm resources and secondary metabolism regulation in Reishi mushroom (Ganoderma lucidum)

Chin Herb Med. 2023 Jun 10;15(3):376-382. doi: 10.1016/j.chmed.2023.01.005. eCollection 2023 Jul.

Authors

Xinyu He¹, Yiwen Chen¹, Zhenhao Li², Ling Fang², Haimin Chen¹, Zongsuo Liang^{1

3}, Ann Abozeid⁴, Zongqi Yang¹, Dongfeng Yang^{1

3}

Affiliations

¹ Key Laboratory of Plant Secondary Metabolism and Regulation of Zhejiang Province, College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.
² Zhejiang Shouxiangu Botanical Drug Institute Co., Ltd., Hangzhou 310018, China.
³ Shaoxing Academy of Biomedicine Co., Ltd. of Zhejiang Sci-Tech University, Zhejiang Engineering Research Center for Development Technology of Medicinal and Edible Health Food, Shaoxing 312000, China.
⁴ Botany and Microbiology Department, Faculty of Science, Menoufia University, Shebin Elkoom 32511, Egypt.

Abstract

Ganoderma lucidum is a valuable medical macrofungus with a myriad of diverse secondary metabolites, in which triterpenoids are the major constituents. This paper introduced the germplasm resources of genus Ganoderma from textual research, its distribution and identification at the molecular level. Also we overviewed G. lucidum in the components, the biological activities and biosynthetic pathways of ganoderic acid, aiming to provide scientific evidence for the development and utilization of G. lucidum germplasm resources and the biosynthesis of ganoderic acid.

Keywords: Ganoderma lucidum (Leyss. ex Fr.) Karst.; chemical constituents; ganoderic acid; germplasm resources; pharmacological activities; secondary metabolism regulation.

Publication types

Review