Editorial: Organoids, organs-on-chip, nanoparticles and in silico approaches to dissect the tumor-immune dynamics and to unveil the drug resistance mechanisms to therapy in the tumor microenvironment

Fabrizio Mattei; Jason T George; Mohit Kumar Jolly

doi:10.3389/fimmu.2023.1253551

Editorial: Organoids, organs-on-chip, nanoparticles and in silico approaches to dissect the tumor-immune dynamics and to unveil the drug resistance mechanisms to therapy in the tumor microenvironment

Front Immunol. 2023 Jul 18:14:1253551. doi: 10.3389/fimmu.2023.1253551. eCollection 2023.

Authors

Fabrizio Mattei¹, Jason T George², Mohit Kumar Jolly³

Affiliations

¹ Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
² Department of Biomedical Engineering, Texas A&M University, College Station, TX, United States.
³ Center for BioSystems Science and Engineering, Indian Institute of Science, Bangalore, India.

No abstract available

Keywords: 3D models; advanced algorithms for immuno-oncology; advanced in vitro models; drug delivery; nanotechnologies; organs-on-chip platforms; personalized medicine for cancer patients; preclinical models.

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

Humans
Microphysiological Systems
Neoplasms*
Organoids
Tumor Microenvironment*

Grants and funding

FM is supported by two grants from NextGenerationEU/MUR/PNRR: Project “HEAL ITALIA” (PE00000019, Miss.4, Comp.2, Invest.1.3, years 2022-2025) and Project “Rome Technopole Foundation” (ECS00000024, Miss.4, Comp.2, Invest.1.5, years 2022-2025). JG is supported by the Cancer Prevention and Research Institute of Texas (CPRIT RR210080). JTG is a CPRIT Scholar in Cancer Research. MJ is supported by Ramanujan Fellowship (SB/S2/RJN-049/2018) awarded by Science and Research Board, Government of India.