Towards a post-pandemic future for global pathogen genome sequencing

PLoS Biol. 2023 Aug 1;21(8):e3002225. doi: 10.1371/journal.pbio.3002225. eCollection 2023 Aug.

Abstract

Pathogen genome sequencing has become a routine part of our response to active outbreaks of infectious disease and should be an important part of our preparations for future epidemics. In this Essay, we discuss the innovations that have enabled routine pathogen genome sequencing, as well as how genome sequences can be used to understand and control the spread of infectious disease. We also explore the impact of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic on the field of pathogen genomics and outline the challenges we must address to further improve the utility of pathogen genome sequencing in the future.

MeSH terms

  • COVID-19* / epidemiology
  • Chromosome Mapping
  • Disease Outbreaks
  • Humans
  • Pandemics
  • SARS-CoV-2* / genetics

Grants and funding

The author(s) received no specific funding for this work.