Long COVID-19 and Insulin Autoimmune Syndrome: A Case Report

Clin Ther. 2023 Sep;45(9):e187-e192. doi: 10.1016/j.clinthera.2023.06.026. Epub 2023 Jul 29.

Abstract

Purpose: To describe a case report of a patient with symptoms associated with metabolic alterations 1 month after having COVID-19.

Methods: Laboratory tests, clinical evaluations, and body composition assessments were performed by specialists.

Findings: The patient presented excessive sweating, hot flashes, dizziness, blurred vision, and seizure. Laboratory tests indicated low glucose levels after convulsions (50, 42.7, and 55 mg/dL), high insulin levels (basal, 638 µIU/mL; 2-hour, >1000 µU/mL), and positivity for anti-insulin antibodies. The patient was diagnosed with insulin autoimmune syndrome. Treatment with azathioprine and nutritional recommendations improved remission.

Implications: SARS-CoV-2 infection or vaccination might induce insulin tolerance failure.

Keywords: Autoimmunity; Azathioprine; Insulin; Long COVID-19; SARS-CoV-2.

Publication types

  • Case Reports