Peripheral Nerve Stimulation for Pain Management: A Review

Curr Pain Headache Rep. 2023 Sep;27(9):321-327. doi: 10.1007/s11916-023-01143-0. Epub 2023 Jul 31.

Abstract

Purpose of review: Peripheral nerve stimulation has seen a recent upsurge in utilization for various chronic pain conditions, specifically from a neuropathic etiology, where a single peripheral nerve can be pinpointed as a culprit for pain.

Recent findings: There is conflicting evidence about the efficacy and long-term outcomes of peripheral nerve stimulation for chronic pain, with most studies being small sized. The focus of this article is to review available evidence for the utilization of peripheral nerve stimulation for chronic pain syndromes as well as upcoming evidence in the immediate postoperative realm. The indications for the use of PNS have expanded from neuropathic pain such as occipital neuralgia and post-amputation pain, to more widespread disease processes such as chronic low back pain. Percutaneous PNS delivered over a 60-day period may provide significant carry-over effects including pain relief, potentially avoiding the need for a permanently implanted system while enabling improved function in patients with chronic pain.

Keywords: Chronic pain; Neuropathic pain; Peripheral nerve stimulation; Postoperative pain.

Publication types

  • Review

MeSH terms

  • Chronic Disease
  • Chronic Pain* / therapy
  • Electric Stimulation Therapy*
  • Humans
  • Neuralgia* / therapy
  • Pain Management
  • Peripheral Nerves
  • Transcutaneous Electric Nerve Stimulation*