A changing gut virome ecological landscape with longevity

Tomasz Wilmanski; Sean M Gibbons

doi:10.1016/j.tim.2023.07.013

A changing gut virome ecological landscape with longevity

Trends Microbiol. 2023 Sep;31(9):882-884. doi: 10.1016/j.tim.2023.07.013. Epub 2023 Jul 28.

Authors

Tomasz Wilmanski¹, Sean M Gibbons²

Affiliations

¹ Amgen, Inc., Thousand Oaks, CA 91320, USA. Electronic address: twilmans@amgen.com.
² Institute for Systems Biology, Seattle, WA 98109, USA; Department of Bioengineering, University of Washington, Seattle, WA 98195, USA; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA; eScience Institute, University of Washington, Seattle, WA 98195, USA. Electronic address: sgibbons@isbscience.org.

PMID: 37517959
PMCID: PMC10485875 (available on 2024-09-01)
DOI: 10.1016/j.tim.2023.07.013

Abstract

A recent study (Johansen et al., 2023) shows how the ecological composition of the human gut virome changes with age, showing a decline in core taxa and an enrichment of subdominant taxa, similar to what has been observed in the gut bacteriomes of centenarians.

Publication types

Research Support, N.I.H., Extramural
Comment

MeSH terms

Aged, 80 and over
Gastrointestinal Microbiome*
Humans
Longevity*
Virome

Grants and funding

R01 DK133468/DK/NIDDK NIH HHS/United States