Definitive weekly hypofractionated radiotherapy in surgery-ineligible older adults with cutaneous squamous cell carcinoma of the head and neck region

Francesca De Felice; Maria Serpone; Carlo Guglielmo Cattaneo; Federico Di Giammarco; Alberto Fallico; Alessia Delle Donne; Maura Lanzilao; Elisa Vitti; Francesco Marampon; Daniela Musio; Vincenzo Tombolini; Giuseppe Minniti

doi:10.1016/j.jgo.2023.101596

Definitive weekly hypofractionated radiotherapy in surgery-ineligible older adults with cutaneous squamous cell carcinoma of the head and neck region

J Geriatr Oncol. 2024 Jan;15(1):101596. doi: 10.1016/j.jgo.2023.101596. Epub 2023 Jul 28.

Affiliations

¹ Radiation Oncology, Policlinico Umberto I, Department of Radiological, Oncological and Pathological Sciences, "Sapienza" University of Rome, Viale Regina Elena 326, 00161 Rome, Italy. Electronic address: fradefelice@hotmail.it.
² Radiation Oncology, Policlinico Umberto I, Department of Radiological, Oncological and Pathological Sciences, "Sapienza" University of Rome, Viale Regina Elena 326, 00161 Rome, Italy.

PMID: 37517887
DOI: 10.1016/j.jgo.2023.101596

Abstract

This study intends to address the impact of weekly hypofractionated radiation therapy with curative intent for cutaneous squamous cell carcinoma of the head and neck region in the elderly population.

Keywords: Cutaneous squamous cell carcinoma; Definitive RT; Elderly; Hypofractionated RT; Radiation therapy; Unfit patients.

MeSH terms

Aged
Carcinoma, Squamous Cell* / radiotherapy
Carcinoma, Squamous Cell* / surgery
Head and Neck Neoplasms* / radiotherapy
Head and Neck Neoplasms* / surgery
Humans
Radiation Dose Hypofractionation
Skin Neoplasms* / radiotherapy
Skin Neoplasms* / surgery
Squamous Cell Carcinoma of Head and Neck / radiotherapy