Intracerebroventricular baclofen therapy improves function and quality of life in a child with severe cerebral palsy

Childs Nerv Syst. 2023 Dec;39(12):3639-3642. doi: 10.1007/s00381-023-06084-y. Epub 2023 Jul 29.

Abstract

Limited therapies are available for severe cerebral palsy children (CP) with complex movement disorders, especially when both dystonia and spasticity are present. In this publication, we present the improvement of a child with severe CP after intracerebroventricular baclofen therapy. The treatment can impact not just the movement disorders but also on the quality of life of the child and caregivers. Global functional improvements can be observed on the 6-month follow-up.

Keywords: Baclofen; Baclofen pump; Cerebral palsy; Intracerebroventricular baclofen; Intraventricular therapy; Spasticity.

MeSH terms

  • Baclofen
  • Cerebral Palsy* / complications
  • Cerebral Palsy* / drug therapy
  • Child
  • Humans
  • Infusion Pumps, Implantable
  • Movement Disorders*
  • Muscle Relaxants, Central*
  • Muscle Spasticity / drug therapy
  • Quality of Life

Substances

  • Baclofen
  • Muscle Relaxants, Central