Human Body-Fluid-Assisted Fracture of Zinc Alloys as Biodegradable Temporary Implants: Challenges, Research Needs and Way Forward

Materials (Basel). 2023 Jul 13;16(14):4984. doi: 10.3390/ma16144984.

Abstract

Alloys of magnesium, zinc or iron that do not contain toxic elements are attractive as construction material for biodegradable implants, i.e., the type of implants that harmlessly dissolve away within the human body after they have completed their intended task. The synergistic influence of mechanical stress and corrosive human body fluid can cause sudden and catastrophic fracture of bioimplants due to phenomena such as stress corrosion cracking (SCC) and corrosion fatigue (CF). To date, SCC and CF of implants based on Zn have scarcely been investigated. This article is an overview of the challenges, research needs and way forward in understanding human body-fluid-assisted fractures (i.e., SCC and CF) of Zn alloys in human body fluid.

Keywords: biodegradable implants; corrosion fatigue; human body fluid; iron alloys; magnesium alloys; stress corrosion cracking; zinc alloys.

Publication types

  • Review

Grants and funding

No funding was received for this work.