Non-Squamous Cell Carcinoma of the Larynx: A State-of-the-Art Review

Carlos M Chiesa-Estomba; Maria Rosaria Barillari; Miguel Mayo-Yáñez; Antonino Maniaci; Nicolas Fakhry; Giovanni Cammaroto; Tareck Ayad; Jerome R Lechien

doi:10.3390/jpm13071084

Non-Squamous Cell Carcinoma of the Larynx: A State-of-the-Art Review

J Pers Med. 2023 Jun 30;13(7):1084. doi: 10.3390/jpm13071084.

Authors

Carlos M Chiesa-Estomba^{1

2}, Maria Rosaria Barillari^{2

3}, Miguel Mayo-Yáñez^{2

4}, Antonino Maniaci^{2

5}, Nicolas Fakhry^{2

6}, Giovanni Cammaroto^{2

7}, Tareck Ayad^{2

8}, Jerome R Lechien^{2

9}

Affiliations

¹ Department of Otorhinolaryngology, Donostia University Hospital, Osakidetza, 20014 San Sebastian, Spain.
² Head & Neck Study Group, Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies (YO-IFOS), 13005 Marseille, France.
³ Division of Phoniatrics and Audiology, Department of Mental and Physical Health and Preventive Medicine, University of L. Vanvitelli, 81100 Naples, Italy.
⁴ Otorhinolaryngology-Head and Neck Surgery Department, Complexo Hospitalario Universitario A Coruña (CHUAC), 15006 A Coruña, Spain.
⁵ Department of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", ENT Section, University of Catania, Via S. Sofia 78, 95125 Catania, Italy.
⁶ Department of Otorhinolaryngology-Head and Neck Surgery, APHM, La Conception University Hospital, 13005 Marseille, France.
⁷ Department of Otolaryngology-Head & Neck Surgery, Morgagni Pierantoni Hospital, 47100 Forli, Italy.
⁸ Division of Otolaryngology-Head & Neck Surgery, Centre Hospitalier de L'Université de Montréal, Montreal, QC H2X 0C1, Canada.
⁹ Department of Otolaryngology-Head & Neck Surgery, Foch Hospital, School of Medicine, UFR Simone Veil, Université Versailles Saint-Quentin-en-Yvelines (Paris Saclay University), 91190 Paris, France.

Abstract

(1) Background: Non-squamous cell laryngeal carcinoma includes endothelial tumors, such as minor salivary gland tumors, lymphoepithelial tumors, neuroendocrine tumors, soft and hard tissue sarcomas, and malignant melanomas. (2) Methods: A state-of-the-art review using the MEDLINE/PUBMED, Google Scholar, Ovid Medline, Embase, and Scopus electronic databases was performed. (3) Conclusions: In order to optimize overall treatment outcomes, a multidisciplinary, patient-centered approach to the management of non-SCC of the larynx must be adopted universally; a national or international registry on non-SCC laryngeal cancer can be useful to improve understanding about the behavior of this kind of tumor.

Keywords: carcinoma; laryngeal; non-squamous; sarcoma.

Publication types

Review

Grants and funding

This research received no external funding.