Pseudokinases, Tribbles Proteins and Cancer

Guillermo Velasco; Wolfgang Link

doi:10.3390/cancers15143547

Pseudokinases, Tribbles Proteins and Cancer

Cancers (Basel). 2023 Jul 9;15(14):3547. doi: 10.3390/cancers15143547.

Authors

Guillermo Velasco^{1

2}, Wolfgang Link³

Affiliations

¹ Department of Biochemistry and Molecular Biology, School of Biology, Complutense University, 28040 Madrid, Spain.
² Instituto de Investigaciones Sanitarias San Carlos (IdISSC), 28040 Madrid, Spain.
³ Instituto de Investigaciones Biomédicas "Alberto Sols" (CSIC-UAM), Arturo Duperier 4, 28029 Madrid, Spain.

Abstract

The human kinome comprises 518 protein kinases, of which approximately 10% lack one or more of the conserved amino acids necessary for catalytic activity [...].

Publication types

Editorial

Grants and funding

This work was supported by the Spanish Ministry of Science, Innovation and Universities through Grant RTI2018-094629-B-I00 to WL. Tribbles-related work in GV laboratory was supported by the Instituto de Salud Carlos III (ISCIII) and confounded by the European Regional Development Fund (ERDF), “A way to make Europe”, grant number PI18/00442 integrated into the State Plan for R & D + I 2017-2020 and grant number PI21/00343 integrated into the State Plan for R & D + I 2021-2023, by the European Commission through the Horizon 2020 European Training Networks program, grant number H2020-MSCA-ITN-308 2016 721532; and by the Breast Cancer Now (formerly Breast Cancer Campaign) foundation, grant number 2012NovSP033.