The definition, diagnosis, and symptoms of the uterine niche - A systematic review

Best Pract Res Clin Obstet Gynaecol. 2023 Aug:90:102390. doi: 10.1016/j.bpobgyn.2023.102390. Epub 2023 Jul 15.

Abstract

Of all neonates, 21% are delivered by cesarean section (CS). A long-term maternal complication of an SC is a uterine niche. The aim of this review is to provide an overview of the current literature on imaging techniques and niche-related symptomatology. We performed systematic searches on imaging and niche symptoms. For both searches, 87 new studies were included. Niche evaluation by transvaginal sonography (TVS) or contrast sonohysterography (SHG) proved superior over hysteroscopy or magnetic resonance imaging. Studies that used SHG in a random population identified a niche prevalence of 42%-84%. Niche prevalence differed based on niche definition, symptomatology, and imaging technique. Most studies reported an association with gynecological symptoms, poor reproductive outcomes, obstetrical complications, and reduced quality of life. In conclusion, non-invasive TVS and SHG are the superior imaging modalities to diagnose a niche. Niches are prevalent and strongly associated with gynecological symptoms and poor reproductive outcomes.

Keywords: Cesarean section; Hysteroscopy; Magnetic resonance imaging; Symptoms; Ultrasound; Uterine niche.

Publication types

  • Systematic Review
  • Review

MeSH terms

  • Cesarean Section* / adverse effects
  • Cicatrix / complications
  • Cicatrix / diagnostic imaging
  • Female
  • Humans
  • Hysteroscopy / adverse effects
  • Hysteroscopy / methods
  • Infant, Newborn
  • Pregnancy
  • Quality of Life*
  • Ultrasonography / methods
  • Uterus / diagnostic imaging