Dimeric (Poly)Hydroxynaphthazarins, Metabolites of Echinoderms and Lichens: The History of the Synthesis and Structure Elucidation

Dmitry N Pelageev; Ksenia L Borisova; Victor Ph Anufriev

doi:10.3390/md21070407

Dimeric (Poly)Hydroxynaphthazarins, Metabolites of Echinoderms and Lichens: The History of the Synthesis and Structure Elucidation

Mar Drugs. 2023 Jul 19;21(7):407. doi: 10.3390/md21070407.

Authors

Dmitry N Pelageev¹, Ksenia L Borisova¹, Victor Ph Anufriev¹

Affiliation

¹ G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Prospect 100 let Vladivostoku 159, 690022 Vladivostok, Russia.

Abstract

This review provides information on the synthesis and revision of the structures of natural dimeric (poly)hydroxynaphthazarins, metabolites of echinoderms and lichens, and on the refinement of the direction and mechanism of reactions in the synthesis of some of these compounds.

Keywords: cuculoquinone; ethylidene-bis(2,6,7-trihydroxynaphthazarin); hybocarpone; islandoquinone; lichens; mesocentroquinone; metabolites; mirabiquinone; octahydroxymethyldibenzo[b,i] xanthenetetraone; sea urchins; tautomerism.

Publication types

Review

MeSH terms

Animals
Echinodermata
Lichens* / chemistry

Grants and funding

This research received no external funding.