Massive, life-threatening hemoptysis due to localized granulomatosis with polyangiitis

Eleonora Coviello; Francesco Puma; Domenico Pourmolkara; Martina Mandarano; Antonio Giulio Napolitano

doi:10.1186/s13019-023-02302-5

Massive, life-threatening hemoptysis due to localized granulomatosis with polyangiitis

J Cardiothorac Surg. 2023 Jul 26;18(1):239. doi: 10.1186/s13019-023-02302-5.

Authors

Eleonora Coviello^{1

2}, Francesco Puma³, Domenico Pourmolkara³, Martina Mandarano⁴, Antonio Giulio Napolitano³

Affiliations

¹ Department of Thoracic Surgery, University of Perugia Medical School, Piazzale Giorgio Menghini 3, Perugia, 06129, Italy. eleonoracoviello@hotmail.it.
² Thoracic Surgery Unit, Department of Surgical Sciences, Santa Maria della Misericordia Hospital, University of Perugia Medical School, Perugia, 06134, Italy. eleonoracoviello@hotmail.it.
³ Department of Thoracic Surgery, University of Perugia Medical School, Piazzale Giorgio Menghini 3, Perugia, 06129, Italy.
⁴ Department of Anatomic Pathology and Histology, University of Perugia Medical School, Piazzale Giorgio Menghini 3, Perugia, 06129, Italy.

Abstract

Massive hemoptysis may be related to a wide spectrum of diseases whose differential diagnosis can be challenging, also due to the medical emergency condition.We present a case of a 33-year-old woman presented to our department with sudden, life-threatening hemoptysis from unknown etiology, which required a rescue pulmonary lobectomy after resuscitation maneuvers. Histology proved to be a localized Wegener granulomatosis. Our case shows that granulomatosis should always be considered among the possible, although rarer, causes of massive hemoptysis.

Keywords: GPA; Hemoptysis; Lobectomy.

Publication types

Case Reports

MeSH terms

Adult
Female
Granulomatosis with Polyangiitis* / complications
Granulomatosis with Polyangiitis* / diagnosis
Hemoptysis* / diagnosis
Hemoptysis* / etiology
Humans
Lung / pathology