Towards further understanding the applications of endophytes: enriched source of bioactive compounds and bio factories for nanoparticles

Nisha Choudhary; Naveen Dhingra; Amel Gacem; Virendra Kumar Yadav; Rakesh Kumar Verma; Mahima Choudhary; Uma Bhardwaj; Rajendra Singh Chundawat; Mohammed S Alqahtani; Rajarshi Kumar Gaur; Lienda Bashier Eltayeb; Waleed Al Abdulmonem; Byong-Hun Jeon

doi:10.3389/fpls.2023.1193573

Towards further understanding the applications of endophytes: enriched source of bioactive compounds and bio factories for nanoparticles

Front Plant Sci. 2023 Jul 10:14:1193573. doi: 10.3389/fpls.2023.1193573. eCollection 2023.

Authors

Affiliations

¹ Dept of Biosciences, School of Liberal Arts and Sciences, Mody University of Science and Technology, Lakshmangarh, Sikar, Rajasthan, India.
² Department of Agriculture, Medi-Caps University, Pigdamber Road, Rau, Indore, Madhya Pradesh, India.
³ Department of Physics, Faculty of Sciences, University 20 Août 1955, Skikda, Algeria.
⁴ Department of Life Sciences, Hemchandracharya North Gujarat University, Patan, Gujarat, India.
⁵ Department of Biotechnology, Noida International University, Noida, U.P., India.
⁶ Radiological Sciences Department, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.
⁷ BioImaging Unit, Space Research Centre, University of Leicester, Leicester, United Kingdom.
⁸ Department of Biotechnology, Deen Dayal Upadhyaya (D.D.U.) Gorakhpur University, Gorakhpur, Uttar Pradesh, India.
⁹ Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Prince Sattam Bin AbdulAziz University- Al-Kharj, Riyadh, Saudi Arabia.
¹⁰ Department of Pathology, College of Medicine, Qassim University, Buraidah, Saudi Arabia.
¹¹ Department of Earth Resources and Environmental Engineering, Hanyang University, Seoul, Republic of Korea.

Abstract

The most significant issues that humans face today include a growing population, an altering climate, an growing reliance on pesticides, the appearance of novel infectious agents, and an accumulation of industrial waste. The production of agricultural goods has also been subject to a great number of significant shifts, often known as agricultural revolutions, which have been influenced by the progression of civilization, technology, and general human advancement. Sustainable measures that can be applied in agriculture, the environment, medicine, and industry are needed to lessen the harmful effects of the aforementioned problems. Endophytes, which might be bacterial or fungal, could be a successful solution. They protect plants and promote growth by producing phytohormones and by providing biotic and abiotic stress tolerance. Endophytes produce the diverse type of bioactive compounds such as alkaloids, saponins, flavonoids, tannins, terpenoids, quinones, chinones, phenolic acids etc. and are known for various therapeutic advantages such as anticancer, antitumor, antidiabetic, antifungal, antiviral, antimicrobial, antimalarial, antioxidant activity. Proteases, pectinases, amylases, cellulases, xylanases, laccases, lipases, and other types of enzymes that are vital for many different industries can also be produced by endophytes. Due to the presence of all these bioactive compounds in endophytes, they have preferred sources for the green synthesis of nanoparticles. This review aims to comprehend the contributions and uses of endophytes in agriculture, medicinal, industrial sectors and bio-nanotechnology with their mechanism of action.

Keywords: bioactive component; endophytes; larvicidal; nano particle; plant growth promotion.

Publication types

Review

Grants and funding

The authors extend their appreciation to the Deanship of Scientific Research at King Khalid University (KKU) for funding this research through the Research Group Program Under the Grant Number: (R.G.P.2/513/44). This work was supported by the Mid-Career Researcher Program (grant no. 2020R1A2C3004237) through the National Research Foundation of the Republic of Korea. The authors are also thankful to the Department of Biosciences; Mody University of Science and Technology, Lakshmangarh Sikar, Rajasthan (SM/2020-21/008 and SM/2022-23/008) for providing financial support.