MRI Imaging Appearance of Hyperostosis Frontalis Interna (HFI): A Case Report of Focal Benign Enhancement

Anish Bhandari; Mark Greenhill; Mayra Anthony; Sorabh Sharma; Raza Mushtaq

doi:10.2174/1573405620666230720103113

MRI Imaging Appearance of Hyperostosis Frontalis Interna (HFI): A Case Report of Focal Benign Enhancement

Curr Med Imaging. 2023 Jul 20. doi: 10.2174/1573405620666230720103113. Online ahead of print.

Authors

Anish Bhandari¹, Mark Greenhill¹, Mayra Anthony², Sorabh Sharma³, Raza Mushtaq¹

Affiliations

¹ Department of Medical Imaging, University of Arizona College of Medicine, 1501 N Campbell Ave, Tucson, Arizona, 85724.
² College of Liberal Arts and Sciences, Arizona State University, 1100 S McAllister Ave, Tempe, AZ 85281.
³ Department of Medicine, University of Arizona College of Medicine, 1501 N Campbell Ave, Tucson, Arizona, 85724.

PMID: 37489785
DOI: 10.2174/1573405620666230720103113

Abstract

Hyperostosis frontalis interna (HFI) is a common and often incidental finding seen on imaging. There is a significant paucity of radiology literature, particularly regarding the MRI imaging appearance of HFI. We reported two cases of HFI on MRI, which showed focal enhancement. These were stable on long-term follow-up studies and thought to be most consistent with benign enhancement. Further studies are needed to elucidate the underlying pathogenesis; however, it is important to be aware that regions of HFI may demonstrate variable enhancement and are sometimes mistaken for osseous metastatic disease.

Keywords: HFI; Hershkovitz grade; Hyperostosis frontalis interna; MRI; focal enhancement; osseous metastatic disease.

Publication types

Case Reports