A Vibrio cholerae O1 outbreak emerged in Haiti in October 2022 after years of cholera absence. In samples from a 2021 serosurvey, we found lower circulating antibodies against V. cholerae lipopolysaccharide in children <5 years of age and no vibriocidal antibodies, suggesting high susceptibility to cholera, especially among young children.
Keywords: Haiti; Vibrio cholerae; antibodies; bacteria; cholera; correlates of protection; dried blood spots; enteric infections; outbreaks; serosurveys; vibriocidal.