Rapid Serologic Test for Diagnosis of Yaws in Patients with Suspicious Skin Ulcers

Emerg Infect Dis. 2023 Aug;29(8):1682-1684. doi: 10.3201/eid2908.230608.

Abstract

The Chembio DPP (Dual Path Platform) Syphilis Screen & Confirm kit (https://chembio.com) is a rapid serologic test that can be used to diagnose yaws. We evaluated its capacity to detect patients with ulcers that tested PCR positive for Treponema pallidum subsp. pertenue. DPP detected 84% of ulcers that were positive by PCR.

Keywords: DPP; Dual Path Platform; Papua New Guinea; Treponema pallidum subsp. pertenue; bacteria; neglected diseases; rapid diagnostic test; skin ulcer; yaws.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Serologic Tests
  • Skin Ulcer* / diagnosis
  • Treponema pallidum / genetics
  • Ulcer / diagnosis
  • Yaws* / diagnosis

Supplementary concepts

  • Treponema pallidum subsp. pertenue