There's more to it: uncovering genomewide DNA methylation heterogeneity

Epigenomics. 2023 Jul;15(13):687-691. doi: 10.2217/epi-2023-0228. Epub 2023 Jul 24.

Abstract

Tweetable abstract Monitoring changes in methylation heterogeneity can be powerful in detecting disease progression early. This editorial highlights the importance of profiling methylation heterogeneity and identifies existing measures and research gaps.

Keywords: bulked methylome; entropy; epialleles; epigenomics; heterogeneity; methylation.

Publication types

  • Editorial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA Methylation*
  • Epigenesis, Genetic*
  • Epigenomics
  • Humans