Latanoprost-associated cystoid macular edema in a patient with phakic eyes

Wei-Che Lin; Jui-Wen Hsieh; Shawn H Tsai; Yu-Wen Lan

doi:10.4103/tjo.tjo_19_22

Latanoprost-associated cystoid macular edema in a patient with phakic eyes

Taiwan J Ophthalmol. 2022 Aug 5;13(2):242-244. doi: 10.4103/tjo.tjo_19_22. eCollection 2023 Apr-Jun.

Authors

Wei-Che Lin^{1

2}, Jui-Wen Hsieh¹, Shawn H Tsai^{1

2

3}, Yu-Wen Lan^{1

2

4}

Affiliations

¹ Department of Ophthalmology, MacKay Memorial Hospital, Taipei City, Taiwan.
² Department of Medicine, MacKay Medical College, New Taipei City, Taiwan.
³ Department of Optometry, MacKay Junior College of Medicine, Nursing, and Management, Taipei City, Taiwan.
⁴ MacKay Junior College of Medicine, Nursing, and Management, Taipei City, Taiwan.

Abstract

Here, we report a case of bilateral cystoid macular edema (CME) in a woman with phakic eyes after 22 years of latanoprost use. Optical coherence tomography revealed multiple intraretinal cysts, and fluorescein angiography revealed characteristic petaloid dye leakage from the perifoveal capillaries. A cause-effect relationship was suspected when CME resolved after switching from latanoprost to dorzolamide, as confirmed by positive rechallenge and dechallenge tests. Since prostaglandin analog-induced CME has only been reported in patients with pseudophakic, aphakic, or phakic eyes with retinal conditions predisposing to macular edema, this seems to be the first reported case of latanoprost-induced CME in a patient with phakic eyes without retinal risk factors.

Keywords: Case report; crystalline lens; cystoid macular edema; latanoprost.

Publication types

Case Reports