False Tendons in the Left Ventricle: Implications for Successful Ablation of Left Posterior Fascicular Tachycardias

JACC Clin Electrophysiol. 2023 Sep;9(9):1914-1929. doi: 10.1016/j.jacep.2023.05.036. Epub 2023 Jul 19.

Abstract

Background: The anatomical substrate for left posterior fascicular ventricular tachycardia (LPF-VT) is still unclear.

Objectives: The purpose of this study is to describe the endocavitary substrate of the re-entrant loop of LPF-VT.

Methods: A total of 26 consecutive patients with LPF-VT underwent an electrophysiology study and radiofrequency ablation.

Results: Intracardiac echocardiography imaging observed a 100% prevalence of false tendons (FTs) at the left posterior septal region in all patients, and 3 different types of FTs could be classified according to their location. In 22 patients, a P1 potential could be recorded via the multielectrode catheter from a FT. In 4 patients without a recorded P1 during LPF-VT, the earliest P2 potentials were recorded from a FT in 3 patients, and from a muscular connection between 2 posteromedial papillary muscles in 1 patient. Catheter ablation focused on the FTs with P1 or earliest P2 (in patients without P1) was successful in all 26 patients. After 19 ± 8.5 months of follow-up, no patients had recurrence of LPF-VT.

Conclusions: FTs provide an electroanatomical substrate for LPF-VT and a "culprit FT" may be identified as the critical structure bridging the macro-re-entrant loop. Targeting the "culprit FT" is a novel anatomical ablation strategy that results in long-term arrhythmia-free survival.

Keywords: false tendon; left posterior fascicular tachycardia; radiofrequency ablation; ventricular tachycardia.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bundle-Branch Block
  • Catheter Ablation* / methods
  • Electrocardiography / methods
  • Electrophysiologic Techniques, Cardiac
  • Heart Ventricles
  • Humans
  • Tachycardia, Ventricular* / diagnostic imaging
  • Tachycardia, Ventricular* / surgery