Case report: Hepatic inflammatory pseudotumor-like follicular dendritic cell sarcoma: a rare case and review of the literature

Shuai Yan; Zhiqiang Yue; Peng Zhang; Liuxia Yuan; Huixuan Wang; Fei Yin; Linglin Ju; Lin Chen; Weihua Cai; Yi Ni; Jinzhu Wu

doi:10.3389/fmed.2023.1192998

Case report: Hepatic inflammatory pseudotumor-like follicular dendritic cell sarcoma: a rare case and review of the literature

Front Med (Lausanne). 2023 Jul 5:10:1192998. doi: 10.3389/fmed.2023.1192998. eCollection 2023.

Authors

Shuai Yan^#¹, Zhiqiang Yue^#¹, Peng Zhang², Liuxia Yuan², Huixuan Wang², Fei Yin³, Linglin Ju², Lin Chen², Weihua Cai⁴, Yi Ni³, Jinzhu Wu⁴

Affiliations

¹ School of Medicine, Nantong University, Nantong, Jiangsu, China.
² Institute of Liver Diseases, Affiliated Nantong Hospital 3 of Nantong University, Nantong, Jiangsu, China.
³ Department of Nail and Breast Surgery, Affiliated Nantong Hospital 3 of Nantong University, Nantong, Jiangsu, China.
⁴ Department of Hepatobiliary Surgery, Affiliated Nantong Hospital 3 of Nantong University, Nantong, Jiangsu, China.

^# Contributed equally.

Abstract

Inflammatory pseudotumor-like follicular dendritic cell sarcoma (IPT-like FDCS) is a rare subtype of follicular dendritic cell sarcoma (FDCS) that primarily occurs in the liver and spleen. The etiology of IPT-like FDCS is unknown, and it has nonspecific clinical manifestations, imaging performance and laboratory test results. Recently, a patient with IPT-like FDCS was admitted to our hospital because of abdominal distension and anemia. Over the past 3 years, the patient has been followed up after a liver mass was found in a physical examination. The lesion gradually enlarged and caused compression symptoms. In November 2022, a tumor with a diameter of approximately 20 cm was found in the right posterior lobe of the liver after abdominal enhanced Magnetic resonance imaging (MRI) in our hospital. Liver tumor biopsy before the operation revealed a large number of hyperplastic plasma cells and a small number of spindle cells, and the spindle cells were atypical. After a complete examination, the patient underwent liver resection. Pathology after surgery confirmed liver IPT-like FDCS.

Keywords: case report; follicular dendritic cell; hepatic; inflammatory pseudotumor; sarcoma.

Publication types

Case Reports

Grants and funding

This study was supported by the Nantong Science and Technology Bureau (Grant/Award Number: JCZ2022080) and the Nantong Municipal Health Commission (Grant/Award Numbers: MSZ2022036, QA20210039, and QN2022041).