Background: Podocyte infolding glomerulopathy (PIG) is a newly described and rare glomerular disease. To date, only approximately 40 cases have been reported globally.
Case summary: A 26-year-old female patient presented to our hospital with a complaint of intermittent edema of both lower limbs over the past 2 years. The patient was diagnosed with PIG. She was prescribed corticosteroid therapy in other hospitals during the initial stage, to which she had responded poorly and had developed femoral head necrosis. Therefore, we administered immunosuppressants, renin-angiotensin system inhibitors, combined with traditional Chinese medicine. The patient was followed for 1 year, during which her clinical condition improved.
Conclusion: Integrated Chinese and Western medicine may be effective for PIG treatment, which requires active intervention to improve prognosis.
Keywords: Case report; Corticosteroid therapy; Immunosuppressive agents; Podocyte-infolding glomerulopathy; Renin-angiotensin system; Traditional Chinese medicine.
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