Anatomical proposal of local anesthesia injection for median nerve block in treating hyperhidrosis with botulinum neurotoxin

Surg Radiol Anat. 2023 Sep;45(9):1083-1087. doi: 10.1007/s00276-023-03199-4. Epub 2023 Jul 20.

Abstract

Introduction: Hyperhidrosis, causing excessive sweat, can be treated with Botulinum neurotoxin injection. Botulinum toxin, an effective and safe treatment for hyperhidrosis, unfortunately involves significant pain due to multiple injections. This study aims to propose a more efficient and less painful approach to nerve blocks for relief, by identifying optimal injection points to block the median nerve, thereby enhancing palmar hyperhidrosis treatment.

Methods: This study, involving 52 Korean cadaver arms (mean age 73.5 years), measured the location of the median nerve relative to the transverse line at the pisiform level to establish better nerve block injection sites.

Results: In between the extensor carpi radialis and palmaris longus, the median nerve was located at an average distance of 47.39 ± 6.43 mm and 29.39 ± 6.43 mm from the transverse line at the pisiform level.

Discussion: To minimize discomfort preceding the botulinum neurotoxin injection, we recommend the optimal injection site for local anesthesia to be located 4 cm distal to the transverse line of the pisiform, within the tendons of the palmaris longus and flexor carpi radialis muscles.

Keywords: Anatomy; Botulinum neurotoxin; Guideline; Hyperhydorsis; Median nerve.

MeSH terms

  • Aged
  • Anesthesia, Local / adverse effects
  • Botulinum Toxins, Type A*
  • Hand
  • Humans
  • Hyperhidrosis* / complications
  • Hyperhidrosis* / drug therapy
  • Median Nerve
  • Pain / etiology

Substances

  • Botulinum Toxins, Type A