First Reported Case of Dulaglutide-Induced Acute Pancreatitis With Normal Serum Lipase Level

Mohammad Shahbazi; Zainab Qudsiya; Aboud Fahel; Afshin Amini; Tariq Tanoli

doi:10.7759/cureus.40576

First Reported Case of Dulaglutide-Induced Acute Pancreatitis With Normal Serum Lipase Level

Cureus. 2023 Jun 17;15(6):e40576. doi: 10.7759/cureus.40576. eCollection 2023 Jun.

Authors

Mohammad Shahbazi¹, Zainab Qudsiya¹, Aboud Fahel¹, Afshin Amini¹, Tariq Tanoli²

Affiliations

¹ Internal Medicine, St. Luke's Hospital, Chesterfield, USA.
² Endocrinology, Diabetes and Metabolism, St. Luke's Hospital, Chesterfield, USA.

Abstract

Dulaglutide is being extensively used for non-insulin-dependent diabetes mellitus and congestive heart failure and is also being used as an off-label weight loss aid. Due to its wide use, we had to shed some light on this rare finding of normal lipase level in a patient with signs and symptoms suggestive of acute pancreatitis. A high index of clinical suspicion for acute pancreatitis despite normal lipase should warrant a low threshold for radiological imaging to rule it out.

Keywords: acute pancreatitis (ap); dulaglutide; exenatide; glp-1 agonist; liraglutide or saxenda; normal lipase pancreatitis; ozempic; semaglutide; trulicity; victoza.

Publication types

Case Reports