Visualization and bibliometric analysis of 3D printing in cartilage regeneration

Front Bioeng Biotechnol. 2023 Jun 30:11:1214715. doi: 10.3389/fbioe.2023.1214715. eCollection 2023.

Abstract

The self-repair ability of cartilage defects is limited, and 3D printing technology provides hope for the repair and regeneration of cartilage defects. Although 3D printing technology and cartilage repair and regeneration have been studied for decades, there are still few articles specifically describing the relationship between 3D printing and cartilage defect repair and regeneration, and a bibliometric analysis has not been completed. To supplement, sort out and summarize the content in related fields, we analyzed the research status of 3D printing technology and cartilage repair and regeneration from 2002 to 2022. According to the set search strategy, the Web of Science Core Collection was used as the data source, and the literature search was completed on December 6, 2022. CiteSpace V and VOSviewer were used as bibliometric tools to complete the analysis of the research focus and direction of the published literature. Based on the analysis results, we focus on the occurrence and development of this field of combined medical and engineering research. Moreover, the current advantages and limitations of this field as well as future development prospects are discussed in depth. It will help to shape researchers' understanding of 3D printing and cartilage repair and regeneration, inspire researchers' research ideas, guide research directions, and promote related research results to clinical application.

Keywords: 3D printing; cartilage regeneration; cartilage repair; tissue engineering; visualization research.

Publication types

  • Systematic Review

Grants and funding

This study was funded by grants from the Natural Science Foundation of Beijing Municipality (7214261), Peking University People’s Hospital Scientific Research Development Funds (RDX2020-02), and Beijing Science and Technology Major Projects (Z181100001818008).