Management of cleft palate among patients with Pierre Robin sequence

Br J Oral Maxillofac Surg. 2023 Sep;61(7):475-481. doi: 10.1016/j.bjoms.2023.06.003. Epub 2023 Jun 20.

Abstract

Pierre Robin Sequence (PRS) is a congenital craniofacial anomaly distinguished by the presence of micrognathia, glossoptosis, and upper airway obstruction. Cleft palate occurs in over 3/4 of patients with PRS. The wide U-shape cleft and airway dysfunction create challenges in clinical management. Currently, disputes exist on the treatment protocol and prognosis of cleft palate management among patients with PRS. This review is focused on the deformity features, intervention timing, technique selection, airway support, and outcome evaluation of cleft palate among patients with PRS, aiming to provide reference to further evolution in the management of PRS-related cleft palate.

Keywords: Airway obstruction; Cleft palate; Growth; Speech; Surgical management.

Publication types

  • Review

MeSH terms

  • Airway Obstruction* / etiology
  • Airway Obstruction* / surgery
  • Cleft Palate* / complications
  • Cleft Palate* / surgery
  • Humans
  • Outcome Assessment, Health Care
  • Pierre Robin Syndrome* / complications
  • Pierre Robin Syndrome* / surgery
  • Prognosis