Complications of e-PTFE Grafts in LDLT; Evaluation of Case Series

Transplant Proc. 2023 Sep;55(7):1598-1604. doi: 10.1016/j.transproceed.2023.03.082. Epub 2023 Jul 12.

Abstract

Background: The expanded polytetrafluoroethylene (ePTFE) grafts are used to drain anterior sector veins during the living donor liver transplantation procedure. We aimed to analyze the potentially life-threatening complications, such as the infection and migration of ePTFE grafts.

Methods: A total of 1264 liver transplantations (LTs) were performed for 1097 adult and 167 pediatric liver failure cases. In total, 1169 living and 95 cadaveric liver transplantation procedures were performed between 2011 and 2021. Right liver transplantation was performed in 1016 cases, including 1002 living donors and 14 cadaveric split right livers. Cadaveric LT was performed in 81 cases.

Results: For 1002 right living liver grafts, 905 vascular grafts were used during the backtable for anterior sector outflow venoplasty. The most commonly drained segments were 5 and 8 (472 cases); there were isolated (5 or 8) and multiple drained segments. Vascular graft migration was described in 7 of 905 (0.77%) patients.

Conclusions: Although complication rates regarding ePTFE grafts are low, there are serious life-threatening causes of morbidity and mortality. We recommend cushioning the vascular graft with the omentum, which is effective in preventing graft migration.

MeSH terms

  • Adult
  • Cadaver
  • Child
  • Hepatic Veins / surgery
  • Humans
  • Liver / blood supply
  • Liver Transplantation* / adverse effects
  • Liver Transplantation* / methods
  • Living Donors
  • Polytetrafluoroethylene / adverse effects
  • Retrospective Studies

Substances

  • Polytetrafluoroethylene