The article "The circRNA-MYLK plays oncogenic roles in the Hep-2 cell line by sponging microRNA-145-5p" by Yao Chen, Yanmei Wang, Congcong Li, Xuechang Li, Tiejun Yuan, Shuqin Yang and Xiaoyan Sun, published in Gen. Physiol. Biophys. 39(3), 2020, pp. 229-237 (doi: 10.4149/gpb_2019060) has been retracted by agreement between the author(s) and journal's Editor in Chief, Prof. Dr. Lubica Lacinova, and AEPresss, s.r.o.. The corresponding author Xiaoyan Sun asked to retract this manuscript as there were some substantial problems in it, which needed more time and research to solve and can more fully re-examine and revise his research results.The authors were not available for a final confirmation of the retraction.